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Oregano Science

Biofilms are structured communities of microorganisms (bacteria, fungi, and sometimes parasites) embedded in a self-produced protective matrix. This matrix helps organisms attach to surfaces, form communities, and shield themselves from antimicrobials and immune defenses. Persister cells are dormant or slow-growing cells within these microbial communities that can survive antimicrobial treatment without being truly drug-resistant. Once treatment is removed, some persister cells may reactivate and help repopulate the infection site.
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Pig studies show that supplementing with oregano oil can be a promising approach for protecting the intestinal barrier by reducing intestinal inflammation harmful bacteria, and inflammatory cytokines, while strengthening the gut barrier. These collective actions help prevent endotoxin leakage into the bloodstream.

Studies support oregano's antibacterial properties, including against antibiotic resistant microbial strains such as: Tuberculosis (TB), Streptococcus (Strep), Staphylococcus (Staph), Escherichia coli (E. coli) and Salmonella.

KEY POINTS:
  • Substantial improvements were shown in the digestive capabilities and overall gut health of chickens fed Origanum minutiflorum.
  • The digestive enzyme activities, in both the pancreas and small intestine, significantly increased in chickens fed Origanum minutiflorum.
  • It was shown that Origanum minutiflorum essential oil may provide a progressive effect on the "quality of the intestines, secretion of digestive enzymes, and particularly the antioxidant defense potential against parasitic infections."
  • Higher, longer and wider villi, as well as decreased crypt depth were observed in the duodenum, jejunum, and ileum areas of the intestines, "providing a greater surface area for nutrient digestion and absorption."
  • These improvements contributed to "increased mucosal enzymes, absorption, and the efficiency of the nutrient transport system."
  • Origanum minutiflorum helped to establish "microbial balance throughout the intestines, enhanced nutrient utilization and gut passage rates (motility), as well as encouraged endogenous digestive enzymatic activity", resulting in an overall "increased intestinal absorptive surface area."1)
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